17a-Hydroxyprogesterone CAS 68-96-2

Iṣaaju 17 α- Hydroxyprogesterone, nigbakan tọka si bi Hydroxyprogesterone (Gẹẹsi: hydroxyprogesterone, OHP), jẹ sitẹriọdu progesterone endogenous ti o jọra si progesterone, ati pe o tun jẹ aṣaaju ti biosynthesis ti ọpọlọpọ awọn homonu sitẹriọdu endogenous, pẹlu androgen, estrogen, glucocorticoid, mineralocorticoid diẹ ninu awọn neurosteroids.Bioactive 17-Hydroxyprogesterone (17-OHP) jẹ progesterone endogenous ati agbedemeji kemikali ninu biosynthesis ti awọn homonu sitẹriọdu miiran.Awọn ẹkọ in vitro 17 α-OHP jẹ progesterone bi agonist olugba olugba chemobookin, botilẹjẹpe ipa rẹ jẹ alailagbara.O tun jẹ agbedemeji kemikali ni biosynthesis ti awọn homonu sitẹriọdu bi androgens, estrogen, homonu ibalopo, glucocorticoids, ati mineralocorticoids.Ninu iwadi vivo 17 Hydroxyprogesterone jẹ inducer sitẹriọdu ti o munadoko fun GVBD (rupture vesicle ibisi).Awọn ohun-ini kemikali crystallization (acetone / hexane).Ojutu yo 221 ℃ (219-220 ℃).[α] 20/D+97 ° (chlorofor